Flagship Projects
These projects differ in system and scale, but together they trace the questions that organize my work: how local context shapes cell state, how tissue injury is interpreted, and how those shifts matter for regeneration and disease.
Research Threads
Mechanobiology and Wound Repair
This is the project closest to the core of my current work: how mechanical changes at a wound edge influence the localization of an epigenetic regulator and help shape repair.
Spatial Transcriptomics and Patient Tissue
This collaborative project let me work at the level of patient tissue, asking how treatment reshapes the immune landscape when viewed with spatial resolution.
Stemness and Signaling
This thread is about what it takes to hold onto stemness in epidermal systems, and how extracellular context and trafficking pathways feed into that decision.
Shared Thread
In different ways, each project asks how context becomes instruction, whether that context is mechanical, extracellular, or tissue-level.
I keep returning to the problem of state change: how cells move, hold, or exit biological states in response to cues around them.
I am interested in work that stays mechanistic without losing tissue relevance, and these projects are where that balance feels most visible in my portfolio.
Where to Start
If you want the fastest entry into how I think, start with the DNMT3A mechanotransduction project. It is the clearest bridge between mechanics, chromatin regulation, and epidermal repair, and it provides the best context for the rest of the portfolio.