DNMT3A mechanotransduction during epidermal injury
This is the project closest to the core of my current work: how mechanical changes at a wound edge influence the localization of an epigenetic regulator and help shape repair.
Flagship Projects
Three projects that best reflect how I think about skin biology
These projects differ in system and scale, but together they trace the questions that organize my work: how local context shapes cell state, how tissue injury is interpreted, and how those shifts matter for regeneration and disease.
Research Threads
Three projects I would want someone to read first
Immune remodeling in vitiligo skin after NB-UVB treatment
This collaborative project let me work at the level of patient tissue, asking how treatment reshapes the immune landscape when viewed with spatial resolution.
Mindin-integrin-STAT3 control of keratinocyte stemness
This thread is about what it takes to hold onto stemness in epidermal systems, and how extracellular context and trafficking pathways feed into that decision.
Shared Thread
What connects these projects for me
Mechanics to molecular state
In different ways, each project asks how context becomes instruction, whether that context is mechanical, extracellular, or tissue-level.
Tissue-state transitions
I keep returning to the problem of state change: how cells move, hold, or exit biological states in response to cues around them.
Regeneration and translational relevance
I am interested in work that stays mechanistic without losing tissue relevance, and these projects are where that balance feels most visible in my portfolio.
Where to Start
Begin with the project closest to my current work
If you want the fastest entry into how I think, start with the DNMT3A mechanotransduction project. It is the clearest bridge between mechanics, chromatin regulation, and epidermal repair, and it provides the best context for the rest of the portfolio.